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Senior Research Associate, Discovery Medicine

BigHat Biosciences - San Mateo, CA, United States - In-office

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BigHat Biosciences is seeking a Senior Research Associate with strong expertise in immunology, cell culture, flow cytometry, and primary cell-based assays to support the functional characterization of lead therapeutic candidates. Key Responsibilities: - Own the functional characterization of therapeutic candidates, driving their development from bench to clinic - Plan, execute, and analyze a range of immunological assays including T cell-dependent cellular cytotoxicity (TDCC), T cell activation assays, cytokine release assays, FACS, ELISA, and antibody-dependent cellular cytotoxicity (ADCC) - Isolate and culture primary immune cells from blood and tissue samples - Interpret experimental results independently and make evidence-based recommendations for program advancement and conceptualization - Maintain detailed, organized records of experimental protocols and results - Present scientific findings clearly to cross-functional teams - Collaborate with a diverse research team to progress scientific objectives in a fast-paced biotech environment Required Qualifications: - B.Sc. in cell biology, molecular biology, biochemistry, genetics, immunology, or related field - Minimum 3 years of relevant research experience, including at least 1 year in industry - Hands-on proficiency in mammalian cell culture and multicolor flow cytometry - Strong scientific curiosity and problem-solving abilities - Ability to work independently and thrive in a dynamic startup environment - Excellent communication skills and collaborative mindset Preferred: - Experience with automation and high-throughput assay platforms Note: BigHat values titles that reflect skill set, organizational impact, and contribution. More experienced candidates are encouraged to apply with understanding that title and responsibilities may be adjusted accordingly.

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