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Senior Accountant - Corporate Accounting

Mineralys Therapeutics, Inc. - Remote - Remote - posted 2026-08-20

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Mineralys Therapeutics is a clinical-stage biopharmaceutical company developing medicines to treat hypertension and related comorbidities including chronic kidney disease, obstructive sleep apnea, and aldosterone-driven diseases. The company is fully remote. The Senior Accountant – Corporate Accounting will play a key role in the monthly close process and support the company's financial closing and accounting operations. This position is responsible for accounting areas including clinical trial and operating expense accruals, prepaids, fixed assets, invoice review, account reconciliations, and financial statement support. Key responsibilities include: **Month-End Close:** Prepare and record monthly journal entries, including operating expense accruals and other recurring close activities. Prepare and maintain account reconciliations and supporting schedules for assigned balance sheet accounts. Investigate and resolve reconciling items timely and accurately. **Clinical Trial & Operating Expense Accruals:** Prepare and record period-end accruals for clinical trial activities, consultants, CROs, CMOs, and other R&D expenditures. Partner with vendors, clinical, CMC, and other business functions to establish processes for obtaining supporting documentation and operational data. Analyze clinical trial activity, contractual commitments, vendor invoices, and operational data to develop accurate accrual estimates. **AP and Invoice Review:** Review vendor invoices for appropriate coding, documentation, and approval. Review prepaid expenditures and ensure appropriate classification. Investigate and resolve invoice discrepancies and aging items. **Prepaid Expenses and Fixed Assets:** Maintain prepaid expense schedules and amortization calculations. Maintain the fixed asset subledger and supporting schedules. Maintain lease accounting schedules and supporting documentation. Review contracts to determine appropriate accounting treatment. **Financial Reporting Support:** Assist with preparation of financial reporting packages. Prepare supporting schedules for financial disclosures. Perform variance analyses and provide explanations of key account fluctuations. Support financial statement audits. **Controls & Process Improvement:** Participate in execution and documentation of internal controls and SOX compliance activities. Identify opportunities to improve accounting processes and close efficiency. Required qualifications: Bachelor's degree in Accounting or Finance; 4+ years of progressive accounting experience; experience in biotechnology, pharmaceutical, or life sciences industry; strong understanding of U.S. GAAP; experience with month-end close, account reconciliations, and supporting audits; advanced Microsoft Excel skills. Preferred qualifications: Experience preparing and analyzing clinical trial accruals and R&D expense accounting; CPA or CPA candidate; public accounting or publicly traded company experience; experience with NetSuite or other large-scale ERP systems.

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