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Nautilus Biotechnology is developing a single-molecule protein analysis platform to democratize access to the proteome and accelerate drug development. The Senior Accountant will be a critical member of the growing accounting team, reporting to the Associate Director of Accounting.
Key responsibilities include executing the monthly accounting close process with journal entries for accruals, prepaids, and general ledger accounts; preparing and reviewing balance sheet reconciliations monthly; maintaining a strong internal control environment in accordance with SOX 404 requirements; and identifying opportunities to improve close efficiency and strengthen controls. You will partner with FP&A and cross-functional teams on accrual estimates and prepaid amortization schedules, support audit preparation, and assist with accounting policy implementation as the company scales from pre-commercial to commercial operations.
The ideal candidate has 4+ years of progressive accounting experience with exposure to general ledger accounting, month-end close, and accounts payable. A degree in Accounting or Finance is required (CPA preferred). You should have solid working knowledge of U.S. GAAP, experience in SOX-compliant environments with controls documentation ownership, and familiarity with enterprise financial systems (NetSuite a plus). Strong Excel skills (VLOOKUP, SUMIFS, Index/Match, pivot tables), analytical ability, and attention to detail are essential. You must be comfortable managing competing deadlines in a fast-paced, high-growth biotech environment, collaborating cross-functionally, and managing remote/offshore relationships. A continuous improvement mindset and flexibility to grow with the company are valued.