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PhaseV is redefining clinical trial design and execution using advanced causal machine learning and generative AI. The company helps biopharma and biotech organizations make faster, more accurate, and efficient development decisions by detecting hidden signals in clinical data and converting them into actionable insights across the trial lifecycle. Headquartered in Cambridge, MA with R&D and medical teams in Tel Aviv, PhaseV is backed by Insight Partners and Accel, has raised $65M to date, and works with top pharmaceutical companies, biotechs, and CROs. The platform has driven reported outcomes including up to 40% reductions in enrollment time, 50% lower trial costs, and 30%+ higher probability of trial success.
The platform comprises four core modules: Response Optimizer (uncovers patient response heterogeneity to identify optimal treatment populations), Trial Optimizer (designs adaptive, Bayesian trial designs tailored to sponsor objectives), Portfolio Optimizer (uses causal graphs to inform portfolio-level development decisions), and Clin Ops Optimizer (applies causal ML to site selection and real-time trial performance).
As Medical Director, you will serve as a key clinical voice across all four product modules, partnering with data scientists, engineers, and product teams internally while engaging directly with pharma, biotech, and CRO clients externally. This is a hybrid role requiring a minimum of 4 days per week in the Tel Aviv office.
Key responsibilities include: providing clinical oversight and interpretation for PhaseV's causal ML-based models across all product modules; ensuring the highest standard of clinical relevance and accuracy in platform outputs and client deliverables; serving as a clinical expert in client-facing discussions, translating data science outputs into actionable medical insights; guiding internal data science, engineering, and product teams on clinical concepts relevant to ongoing projects; partnering with the business development team to communicate PhaseV's clinical value proposition to partners; participating in client meetings, partnership discussions, and proposal development as a clinical subject matter expert; developing and refining presentation content for BD meetings, pitches, and scientific discussions; partnering with product and data science teams to inform new platform capabilities; providing clinical feasibility input during early-stage product ideation and design; and helping define clinically meaningful use cases, endpoints, and success criteria for new offerings.
You will work at the frontier of clinical trial innovation where your work directly shapes how drugs are developed and approved, alongside a world-class team of data scientists, clinicians, and operators. The role offers a diverse, intellectually demanding problem set with no two projects alike, highly collaborative flat startup culture with meaningful ownership and career growth, and exposure to a dual-continent presence (Boston + Tel Aviv) with a global client base.
REQUIREMENTS:
Required:
- M.D. degree
- Excellent communication and presentation skills; comfortable in scientific, business development, and executive-level settings
- Fluent in English
- Ability to thrive in a fast-paced, interdisciplinary startup environment
- Curiosity and willingness to engage with advanced biostatistics and causal machine learning (technical expertise not required)
Preferred:
- Experience supporting business development efforts
- Experience in pharmaceutical, biotech, or CRO environments
- Experience in health technology, AI in healthcare, or related fields
- Track record of thought leadership: publications, conference presentations, or industry writing
- Prior exposure to adaptive trial design, Bayesian methods, or AI/ML in clinical settings
- Working knowledge of clinical trial methodology and regulatory frameworks (FDA, EMA, GCP)
- A second advanced degree (Ph.D. or MBA)
