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Salary: USD 330,000 - 370,000 / annual
Enveda is seeking a Clinical Development Director to lead the clinical strategy for a first-in-class therapeutic candidate with potential across metabolism and autoimmune disease. This is a critical leadership role on the Asset team where you will own the core clinical development plan, design the first-in-human program, and build the regulatory pathway to transform a novel mechanism into a potentially transformational medicine across two therapeutic areas.
Key responsibilities include:
- Build the clinical development plan and first-in-human strategy from the ground up
- Design the Phase 1 protocol, including dose, endpoints, population, pharmacodynamic readouts, and operational considerations for testing across two therapeutic areas
- Shape the translational and biomarker strategy to turn preclinical mechanism into credible human proof-of-mechanism readout
- Support the path to IND and early regulatory strategy
- Run Advisory Boards that produce decision-grade insight and inform trial design
- Build the KOL and site network ahead of clinical initiation
- Engage thought leaders, physicians, PIs, and patients about the opportunity
- Contribute to platform narrative for investors and partners
Enveda is a clinical-stage, AI-enabled biotech company that recently raised $311M in Series E funding. The company has been recognized by Forbes as one of America's Best Startup Employers and by Newsweek as a Top 100 Most Loved Workplace.
QUALIFICATIONS:
- MD with credentials that add actual and perceived credibility to the program
- Live, warm global KOL and site network in autoimmune disease (metabolic disease experience is a plus)
- Track record of taking assets into the clinic and landing non-trivial first-in-human and early-phase programs; experience with design-creative studies is valued
- First-hand experience designing and running early clinical development, particularly proof-of-mechanism studies in immune-mediated disease
- Comfortable owning translational and pharmacodynamic strategy, not just trial logistics
- Clinically creative with strong strategic and scientific judgment
- Demonstrated commitment to patient advocacy and paradigm-shifting approaches
- Well-regarded in the community for substantive expertise
- Entrepreneurial mindset: comfortable with ambiguity, energized by building, motivated by impact
- Collaborative, direct communication style; ego-lite culture fit
