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Senior Technical Project Manager

HeartFlow - San Francisco, CA, United States - Hybrid - posted 2026-10-05

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Salary: USD 163,000 - 185,000 / annual

HeartFlow is a publicly traded medical technology company (HTFL) pioneering AI-driven solutions for coronary artery disease diagnosis and management. The company's flagship product, HeartFlow FFR_CT Analysis, is a non-invasive cardiac test that provides 3D models of coronary arteries to help clinicians assess blood flow impact. The product is cleared for use in the US, UK, Europe, Japan, and Canada, and has been deployed for over 750,000 patients worldwide. The Senior Technical Project Manager will direct and coordinate complex cross-functional projects across engineering and product development, serving as the primary point person for large-scale initiatives. This role carries significant responsibility for planning, execution, and delivery oversight while ensuring strict adherence to design controls and regulatory compliance processes. Key responsibilities include: serving as the primary point person for complex cross-functional projects; overseeing detailed planning, coordination, execution, and delivery; identifying workflow bottlenecks and implementing automation to improve efficiency; proactively identifying and resolving cross-team dependencies with emphasis on risk mitigation; holding teams accountable with clear performance standards; maintaining FDA audit readiness with focus on Design Controls, Software Validation, and Quality Management System Regulation (QMSR) standards; leading audit follow-ups and managing medical-grade certification processes; managing Jira for controlled spaces with full traceability from requirements to verification per IEC 62304; coaching product development teams on best practices; leading integration of AI-first initiatives into engineering workflows; and ensuring projects align with program objectives and strategic goals. The role requires strategic perspective across multiple complex projects at the release level, with guidance and mentorship responsibilities across teams. The incumbent will exercise judgment in selecting methods and techniques for obtaining results, often operating with general instructions on new projects and requiring only occasional supervision. REQUIREMENTS: - Bachelor's degree in Engineering, Business, or related field - 5+ years as a TPM, Project Manager, or Release Manager within a software development organization - Proven ability to construct detailed plans for complex software development projects, ensuring items, dependencies, and risks are proactively identified, managed, and communicated - Proven ability to leverage AI agents, LLMs, and low-code/no-code tools to rapidly build automation that replaces manual workflows and streamlines internal tooling - Proven experience managing audits (SOC2, ISO 27001, etc.) and using audit tools - Advanced Jira Administration skills, including workflow customization and permission management - Ability to translate complex data into actionable insights using process metrics and tracking tools - Exceptional ability to coordinate across diverse technical teams and translate platform needs into business value - Strong written and verbal communication skills, with ability to tailor communication to various audiences including technical teams and senior management - Outstanding organizational skills including ability to prioritize tasks efficiently across multiple complex projects and deadlines with high attention to detail - Strategic problem solver who proactively identifies, anticipates, and mitigates risks and impediments - Team player with proven ability to influence, negotiate, and build consensus across diverse teams and stakeholders

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