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Client Growth & Success Principal Manager- Enterprise Accounts

Twin Health - Remote - Remote - posted 2026-10-16

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Salary: USD 150,000 - 175,000 / annual

Twin Health is seeking a Principal Manager, Client Growth & Success to lead strategic partnerships with large, complex enterprise organizations. Twin Health applies AI Digital Twin technology to metabolic health, helping people prevent and manage chronic diseases like type 2 diabetes and obesity. The company has raised over $100 million, including a $53 million Series E in 2025, and is backed by leading venture firms including Sequoia, Sofina, and Temasek. In this role, you will serve as the strategic point of contact for enterprise clients, building and maintaining trusted relationships with executive, HR, benefits, clinical, and operational stakeholders. You will navigate complex organizational structures, align divergent priorities, and act as a high-impact strategic consultant. Key responsibilities include: **Delivering Exceptional Client Value:** Build deep expertise in Twin Health's programs, clinical operations, and implementation processes. Provide data-driven, consultative recommendations to improve program adoption, member engagement, and clinical outcomes. Prepare and deliver compelling executive business reviews and ROI analyses tailored to each client's goals. Proactively monitor client health, identify risks, and develop mitigation strategies. Drive momentum with clients operating on long decision cycles by bringing recommendations and next steps rather than waiting for client initiation. Influence adoption across multidisciplinary stakeholder groups and turn high-performing clients into brand advocates. **Driving Adoption & Engagement:** Develop and execute strategies that maximize program adoption, stakeholder engagement, and member participation. Leverage data and performance insights to identify optimization opportunities. Collaborate with Marketing to develop client success stories and case studies. Support and lead client events, webinars, and strategic initiatives. **Growing Revenue & Renewals:** Own and manage the full client renewal lifecycle for your portfolio. Identify and secure expansion and upsell opportunities by aligning Twin Health solutions with evolving client priorities. Surface and communicate renewal or expansion risks early while partnering cross-functionally to develop mitigation plans. **Leading Cross-Functional Collaboration:** Coordinate across Implementation, Clinical, Product, Analytics, Marketing, and Business Development to deliver exceptional client experiences. Partner with client leaders to identify opportunities for workflow optimization and strategic growth. Demonstrate ownership and accountability by proactively solving problems and operating with urgency. **Requirements:** - 8+ years of experience in Client Success, Strategic Account Management, Consulting, Partnership Management, or similar client-facing role within healthcare - Experience supporting large, complex enterprise organizations strongly preferred - Proven track record of building strategic client partnerships that drive adoption, client retention, revenue growth, and long-term business value - Experience managing highly matrixed enterprise organizations with multiple executive, clinical, operational, and technical stakeholders - Strong understanding of benefits design, healthcare delivery models, clinical operations, population health, and value-based care principles - Exceptional relationship-building, communication, presentation, and executive influencing skills - Strong analytical, strategic thinking, and problem-solving abilities with ability to translate data into actionable recommendations - Demonstrated ability to influence without direct authority and successfully lead cross-functional initiatives across diverse stakeholder groups - Highly organized with exceptional attention to detail, accountability, and follow-through - Comfortable navigating ambiguity while balancing multiple priorities in fast-paced, evolving environment - Collaborative mindset and passion for delivering measurable client outcomes - Willingness and ability to travel as needed - Experience scaling programs across large, geographically distributed populations during periods of growth or expansion preferred - Must be authorized to work for any employer in the U.S.; unable to sponsor or take over sponsorship of employment visa

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