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Applied Machine Learning Scientist

Unlearn.AI - San Francisco, CA, USA - In-office - posted 2026-08-17

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Unlearn.AI is transforming clinical development by using AI, data science, and digital twins to make pharmaceutical trials faster, more robust, and more scientifically rigorous. The company partners with biopharmaceutical companies to redesign how clinical trials are planned, run, and analyzed. Founded in 2017 and headquartered in San Francisco, Unlearn has raised $50M+ in venture capital from top-tier investors including Altimeter, Insight Partners, and DCVC. As an Applied Machine Learning Scientist, you will lead the development of state-of-the-art ML approaches for generating Digital Twins—probabilistic models that predict a patient's future health outcomes based on their current and past medical history. You'll work with a team of world-class ML scientists and take end-to-end ownership of your mission, investigating broadly to find the right tools and techniques. Key responsibilities include: - Design and implement machine learning models to characterize and predict disease progression - Apply and fine-tune proprietary architectures to real-world clinical data - Clearly communicate technical findings to internal and external stakeholders - Stay current with ML field developments to inform Unlearn's modeling work - Represent Unlearn to the broader scientific community Minimum qualifications: - B.S. in computer science, engineering, physics, mathematics, or related field - 2+ years developing ML models and adapting them to real-world problems - Strong software engineering fundamentals - Fluency in Python ML and data science ecosystem - Proven track record executing ML projects in academic or industrial settings - Demonstrated intellectual curiosity and independent exploration of new techniques Bonus experience includes contributions to open-source ML tools, expertise in unsupervised learning, EBM, NLP, LLMs, optimization theory, or reinforcement learning, prior healthcare/clinical ML work, and AWS familiarity. Unlearn offers meaningful equity, 100% company-covered health insurance, 401k matching, flexible PTO, annual company break, commuter benefits, and paid parental leave.

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