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VP of Engineering

Unlearn.AI - San Francisco, CA, USA - In-office - posted 2026-09-17

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Unlearn.AI is transforming clinical development by using AI, data, and digital twins to enable faster, more robust clinical trials. The company partners with biopharmaceutical companies to redesign how trials are planned, run, and analyzed. Founded in 2017 by machine learning scientists and headquartered in San Francisco, Unlearn has raised $50M+ in venture capital from top-tier investors including Altimeter, Insight Partners, and DCVC. As VP of Engineering, you will lead Unlearn's entire engineering function, including core engineering, applications, ML/AI Ops, and infrastructure teams. The organization spans multiple experience levels anchored by strong senior technical leaders. You will own the quality, reliability, compliance, and security of systems powering the company's AI-heavy, tech-enabled services. Key responsibilities include: - Leading the engineering function across technical disciplines, ensuring AI tools and systems drive efficiency and impact - Driving execution by defining projects, scoping work with teams, and running delivery practices that convert commitments into shipped products - Translating company strategy into engineering roadmaps that sequence work across data, modeling, applications, compliance, and security - Operating as a member of the leadership team, reporting on engineering progress, capacity, and risk while maintaining aligned expectations - Establishing an AI-centric engineering culture that scales organizational impact and equips team members with modern toolsets - Owning hiring and team design, deliberately growing the organization aligned with company needs You will partner closely with Product, Delivery, and R&D teams to understand requirements, integrate engineering with customer delivery teams, and build platforms and tools that enable their success. This is an execution-focused role in a regulated, compliance-heavy environment where engineering plays a critical role in delivering AI technology through models, applications, and agentic systems. REQUIREMENTS: - 10+ years in software engineering with significant experience leading engineering organizations at Senior Director or VP level, including managing managers and senior technical leaders across multiple disciplines - Track record of strong execution in highly collaborative, cross-functional environments where engineering delivered on business-critical timelines - Experience leading across the full stack: infrastructure/DevOps, backend/platform engineering, and application/front-end development - Experience in regulated environments where compliance is a key factor in system design - Demonstrated ability to translate company strategy into engineering roadmaps, communicate priorities, and hold teams accountable for delivery - Experience partnering with Product, R&D, and customer-facing delivery teams; proven track record building internal tools and platforms that measurably improved technical team effectiveness - Experience in growth-stage or early-stage companies building engineering processes and delivery discipline while shipping - Plus: experience in life sciences, healthcare, or other regulated, data-intensive domains

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