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Salary: USD 148,000 - 172,500 / annual
Vaxcyte is a clinical-stage vaccine innovation company developing high-fidelity vaccines to protect against bacterial diseases including invasive pneumococcal disease, Group A Strep, and Shigella. The company is seeking a Systems Engineer to design, deploy, and maintain the systems and infrastructure supporting the organization.
In this role, you will work within the Systems Engineering team, administering core cloud, SaaS, and network technologies, contributing to technical projects, and providing escalated support. This is a hands-on position for an engineer who takes ownership and wants to develop expertise across a modern, cloud-first environment.
Key responsibilities include:
- Install, configure, and maintain cloud servers, workstations, lab infrastructure, and networks
- Administer and support core SaaS and infrastructure technologies including Okta, M365, Microsoft Intune, Proofpoint, Zoom, Meraki, vSphere, and Proxmox
- Implement, manage, and troubleshoot security measures and cybersecurity initiatives
- Contribute to IT projects and initiatives, executing assigned workstreams and collaborating with senior engineers on complex efforts
- Monitor, maintain, and troubleshoot office infrastructure, SaaS applications, and network services (DNS, DHCP, NTP)
- Contribute to automation of manual and recurring tasks
- Perform system deployments, migrations, and application lifecycle activities
- Provide Tier 2/Tier 3 support and serve as technical resource for IT Operations team
- Participate in cross-functional technical projects with other teams
- Create and maintain clear documentation of IT procedures, configurations, and policies
- Participate in pre-scheduled after-hours support for special projects or events
- Assist in administering enterprise AI platforms (Microsoft 365 Copilot, ChatGPT/Claude Enterprise) including user provisioning, access, and configuration
- Help configure and maintain integrations between AI platforms and internal systems such as SSO/identity and data connectors
- Follow and help implement AI security and governance practices
Reports to: Senior Director, IT Operations & Infrastructure
Work Arrangement: Onsite minimum 4 days per week
Requirements:
- Bachelor's degree in computer science or related field, OR equivalent practical experience with minimum 5+ years of relevant IT/systems engineering experience (biotech experience is a plus)
- Working knowledge of foundational IT applications such as Okta, M365, Zoom, and Microsoft Intune/MEM
- Experience administering cloud servers, workstations, and networks, including familiarity with Layer 2/Layer 3 networking and services such as DNS, DHCP, and NTP
- Experience with server administration, network administration, and security administration
- Some experience with scripting (PowerShell, Python) and/or automating manual workstreams
- Exposure to administering or supporting enterprise AI tools is a plus
- Systematic problem-solving approach, strong communication skills, and sense of ownership and drive
- Ability to create clear documentation, adapt and learn new skills, and stay current with developments in the field
- Ability to work under pressure and meet deadlines
