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Senior Scientist, Analytical Development

Asimov - Boston, MA, USA - In-office - posted 2026-09-24

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Asimov is developing a mammalian synthetic biology platform to enable the design and manufacture of next-generation therapeutics. We are seeking a Senior Scientist to join our Analytical Sciences team to lead analytical development efforts supporting the characterization of antibodies, diverse antibody formats (bispecifics, multispecifics, Fc-fusions, engineered architectures), proteins, and cell and gene therapy (CGT) therapeutics. In this role, you will lead analytical development for key projects, designing and implementing experiments to generate actionable results. You will engage with cross-functional teams to share findings, raise critical analytical issues, and support aligned decision-making. You will manage and mentor junior scientists, focusing on experimental design, problem-solving, and fostering a culture of scientific rigor. You will ensure transparency and maintain consistent communication with project stakeholders about progress, risks, and results. You will continuously develop and apply technical skills in analytical method development—including HPLC/UPLC, MS, CE, and other protein characterization techniques—to address evolving project needs. You will identify opportunities to improve workflows, analytical throughput, and reproducibility, and apply your expertise to address complex analytical challenges. Asimov's culture emphasizes recombination: bringing together diverse teams with mixed backgrounds and perspectives to advance synthetic biology as a fully-fledged engineering discipline. REQUIREMENTS: - Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 4+ years of relevant biopharma analytical experience, OR M.S. with 7+ years of relevant experience. - Hands-on experience in analytical method development (HPLC/UPLC, MS, CE, UV, etc.) across diverse antibody formats, with willingness and aptitude to rapidly expand technical expertise. - Strong understanding of antibody structural formats and how format-specific architecture (bispecifics/multispecifics, Fc-fusions, biosimilars, engineered constructs) shapes analytical strategy and method selection. - Experience mentoring junior scientists, guiding them in experimental design and problem-solving, and fostering a culture of rigorous science. - Proactive problem-solving mindset with ability to apply analytical skills to address complex project challenges. - Experience engaging across teams and functions, influencing decisions through effective data-driven communication. - Strong collaboration and alignment skills, with ability to communicate findings clearly and maintain transparency with stakeholders. - Excellent written and verbal communication skills.

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