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Senior Research Associate, Discovery Pharmacology

Altos Labs - Redwood City, CA, United States - In-office - posted 2026-08-25

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Salary: USD 109,200 - 140,000 / annual

Altos Labs is a biotech company on a mission to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and disabilities. The company has been named one of the Top 3 Biotech Companies and ranked on the Forbes 2026 Best Startups in America list. You will join the Discovery Pharmacology team as a Senior Research Associate, supporting critical drug discovery and development projects by executing a wide range of biological and bioanalytical assays. This role is approximately 80% benchtop science work. Key responsibilities include: - Execute drug discovery and development projects independently and collaboratively with the scientific manager - Culture and maintain mammalian cells, manage reagents and working stocks, and contribute to lab maintenance - Design, optimize, automate, execute, and troubleshoot cellular, biochemical, and complex in vitro bioassays - Standardize and optimize assay protocols and draft assay SOPs - Document assay methods, raw data, and results in electronic laboratory notebooks (ELN) ensuring reproducibility and data integrity - Present data at project team meetings to support decision-making Required qualifications: - BS or MS in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or related discipline - Minimum 5 years of industry experience in drug discovery and/or development - Strong expertise in AAV gene therapy technical methods, cellular transduction assays, genome titration (qPCR, ddPCR), transgene expression analysis, and protein analysis (Western Blot, ELISA, capillary electrophoresis) - Hands-on experience developing and performing analytical and bioassays with data analysis and statistical expertise - Experience with state-of-the-art assay technologies (MSD, HTRF, AlphaLISA, Luminex) - Hands-on experience with automation instruments (Bravo, Echo, I.DOT, digital dispensers) - Proficiency in ELN documentation - Excellent data presentation, oral, and written communication skills - Detail-oriented, organized, flexible, and capable of multitasking in fast-paced environments Preferred qualifications include experience across diverse therapeutic modalities (viral gene therapy, mRNA-LNP, nucleic acid therapeutics, small molecules), background in aging/rejuvenation biology, and familiarity with assay qualification criteria and SOP authoring.

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