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Salary: USD 180,000 - 200,000 / annual
Mirum Pharmaceuticals, a biopharmaceutical company focused on rare disease treatments, is seeking a Senior Manager, Program Management to lead integrated drug development programs from preclinical through commercialization.
In this role, you will partner with the Program Lead and cross-functional Development Team to shape and execute integrated program strategy and long-range plans. You will drive team alignment and disciplined execution across scope, schedule, risks, issues, budget, resources, governance, and stakeholder communications. The position connects research, CMC, nonclinical, clinical, regulatory, and commercial functions to ensure clear goals, informed decisions, and coordinated delivery of key program milestones.
Key responsibilities include:
- Developing, maintaining, and executing cross-functional program strategy and integrated development plans
- Establishing and maintaining functionally integrated program schedules with critical path analysis, dependencies, milestones, and resource constraints
- Identifying, assessing, and tracking program risks and issues; facilitating mitigation and contingency planning
- Supporting scenario planning around key milestones and decision points to evaluate trade-offs and identify acceleration opportunities
- Connecting short-, mid-, and long-term plans across functions and highlighting interdependencies and potential impacts
- Facilitating cross-functional team and governance meetings with agenda development, decision framing, and documentation
- Driving timely, transparent program reporting for stakeholders and leadership
- Building strong relationships with functional partners across all development areas
- Serving as a Program Management subject matter resource and contributing to evolution of PM tools and processes
- Providing coaching, mentorship, or oversight to other Program Management staff
The ideal candidate will be a collaborative team member who creates clarity, accountability, and alignment across diverse functional perspectives. You should be a pragmatic problem solver who anticipates challenges, frames options, and drives action. You will connect program-level decisions to portfolio and company priorities and communicate with transparency to different audiences, including senior leaders.
QUALIFICATIONS:
- BA/BS in life sciences with 5+ years of multidisciplinary pharmaceutical or biotechnology industry experience in program management; OR master's or PhD degree with 4+ years of relevant experience
- Experience supporting drug development programs through key clinical and/or regulatory milestones with demonstrated knowledge of the drug development process
- Demonstrated understanding of program and project management practices, tools, and methodologies, including integrated planning, critical path analysis, risk management, scenario planning, and status reporting
- Ability to facilitate cross-functional teams, manage conflict, build consensus, and promote timely, high-quality decision making without direct authority
- Excellent communication, facilitation, problem-solving, analytical thinking, stakeholder management, and organizational skills
- Ability to independently manage multiple priorities, objectives, timelines, and deadlines across programs or workstreams
- Proficiency with planning tools such as Microsoft Project or comparable project management software (desired)
- Experience with AI tools use or implementation (desired)
- PMP certification (preferred but not required)
