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Salary: USD 280,000 - 315,000 / annual
Mirum Pharmaceuticals, a biopharmaceutical company focused on rare diseases, seeks a Senior Director of New Product Planning to shape the company's future portfolio and drive commercial strategy for pipeline assets.
Reporting to the SVP of Corporate Development and Strategy, you will lead commercial strategy for pre-Phase 3 programs while partnering closely with Research, Clinical Development, Medical Affairs, US and International Commercial, Business Development, Corporate Strategy, and Finance. The role bridges science and strategy to identify new indications, evaluate portfolio opportunities, and shape clinical development and investment decisions aligned with unmet need, competitive landscape, and strategic value drivers.
Key responsibilities include:
**Business Development & External Innovation:**
- Lead commercial assessments of licensing, acquisition, and partnership opportunities, integrating scientific rationale, unmet need, clinical profile, competitive landscape, commercial potential, pricing, market access, and strategic fit
- Conduct primary and secondary market research to develop patient-based forecasts, scenario analyses, and risk-adjusted valuations supporting investment and transaction decisions
- Partner with Business Development, R&D, Finance, and US and Global Commercial throughout opportunity evaluation and diligence
**Pipeline & Lifecycle Strategy:**
- Serve as commercial strategy lead on cross-functional product teams for pre-Phase 3 pipeline programs
- Develop business cases and commercial strategies for pipeline assets, including indication prioritization, Target Product Profiles, patient segmentation, value story, competitive differentiation, market opportunity, and lifecycle planning
- Partner with Research, Clinical Development, Market Access, and Medical Affairs to incorporate commercial considerations into development strategy
- Partner with US and Global Commercial leaders to ensure effective transition of assets into late-stage commercial planning
**Portfolio & Corporate Strategy:**
- Evaluate new therapeutic areas and disease spaces by integrating disease biology, unmet need, competitive dynamics, development feasibility, and commercial potential
- Shape portfolio and corporate strategy by identifying growth opportunities, strategic gaps, and priorities for investment and resource allocation
- Own commercial assumptions informing long-range planning for all pre-Phase 3 programs
- Monitor scientific, clinical, competitive, regulatory, and market developments and translate implications for product and portfolio strategy
**Requirements:**
- 10+ years of experience in biotechnology or pharmaceutical industry, including significant experience in New Product Planning, Commercial Strategy, Portfolio Strategy, Business Development, Business Analytics, Marketing/Market Access, or related roles
- Strong scientific acumen with demonstrated ability to understand disease biology, molecular pathways, mechanisms of action, and clinical data, translating them into commercial and development strategy
- Experience shaping strategy for pipeline assets, preferably during early and mid-stage clinical development
- Experience evaluating new indications, lifecycle opportunities, new therapeutic areas, and/or external innovation opportunities
- Strong experience with commercial forecasting, primary and secondary market research, business cases, and asset valuation
- Demonstrated ability to influence senior leaders and cross-functional teams without direct authority
- Ability to communicate complex scientific, clinical, and commercial concepts effectively to scientific experts and senior executives
**Preferred Qualifications:**
- PhD or MD strongly preferred; other advanced scientific or medical degrees with relevant experience considered
- Experience in rare disease and/or specialty therapeutics
- Experience collaborating with global commercial teams and working across multiple therapeutic areas
- Experience supporting licensing, acquisition, or other business development transactions
- Experience presenting strategic recommendations to Executive Leadership and governance committees
