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Salary: USD 126,700 - 171,500 / annual
10x Genomics is seeking a Consumables NPI Engineer 3 to join the Manufacturing Systems Engineering (MSE) team. This role is central to the commercialization and lifecycle management of consumable products within Global Operations Engineering. You will work cross-functionally with Microfluidics, Supply Chain Management, and New Product Development to transfer new plastic components to volume manufacturing, improve robustness and efficiencies across product lines, and provide technical stewardship for on-market products.
Key responsibilities include:
**Cross-Functional Collaboration:** Communicate NPI status, risks, and technical decisions to stakeholders across Operations, R&D, and Commercial teams. Support the Design for Manufacturability (DFM) feedback loop with R&D during transfer of new plastic components into manufacturing.
**Supplier Support & Qualification:** Serve as the primary engineering point of contact for consumables suppliers during design, development, and transfer of new products. Drive qualification activities including IQ/OQ/PQ, first-article inspection, and capability studies. Partner with Supply Chain Management to manage supplier relationships and provide on-site engineering support as needed. Support supplier corrective actions and process changes to ensure yield, quality, and reliability targets are met. Provide lifecycle management support for on-market products.
**Part Release & Change Control:** Own the part release process for new consumable components and assemblies, driving parts through ECOs/ECRs and change control to production status. Coordinate release readiness across engineering, quality, and supply chain gates. Maintain accurate revision control and documentation throughout the release lifecycle.
**BOM & Part Structure:** Build and maintain BOM and part structures in Arena PLM and Oracle ERP for new consumable products. Ensure accuracy of part numbers, revisions, and where-used relationships. Partner with Planning and Manufacturing to structure BOMs that reflect real production and supply chain flow. Troubleshoot and resolve BOM/part structure discrepancies.
**Manufacturing Documentation:** Author and maintain Work Instructions (WINs) for consumable manufacturing and inspection processes. Translate engineering specifications and process knowledge into effective, operator-ready work instructions. Support operator training and continuous improvement of documentation.
**Requirements:**
- Education: BS/MS in Mechanical, Manufacturing, Plastics, or Industrial Engineering
- Experience: 6+ years (BS) or 4+ years (MS) in manufacturing or NPI engineering, ideally within biotech, life sciences, or medical device industries
- PLM/ERP: Demonstrated experience building BOM/part structures and managing part release using PLM (e.g., Arena) and ERP (e.g., Oracle) systems
- Supplier Engineering: Experience qualifying and supporting suppliers (molding, machining, or assembly), including hands-on/on-site engineering support
- Plastics: Direct experience with injection molding, LSR-thermoplastic assemblies, or precision plastics manufacturing, including direct experience in IOPQ planning and execution
- Documentation: Experience authoring work instructions or manufacturing documentation in a quality-controlled environment
- Change Control: Familiarity with ECO/ECR processes and engineering change management
- Technical Foundation: Working understanding of 3D mechanical design, GD&T per ASME Y14.5, dimensional tolerancing, and process capability (Cpk/Ppk) analysis
- Strong written and oral communication skills; ability to work cross-functionally across engineering, quality, and operations
