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Isomorphic Labs is an AI-driven drug discovery company applying frontier machine learning to accelerate scientific breakthroughs and develop life-changing medicines. The company was launched in 2021 to advance human health by building on the Nobel-winning AlphaFold system, combining drug discovery expertise with machine learning specialists to create powerful predictive and generative AI models.
As Senior Finance Business Partner for Drug Design and Development, you will serve as the dedicated financial partner to the drug discovery organization, providing both strategic and operational finance support. This is a new role based in London, supporting the team as Isomorphic Labs builds its drug portfolio and advances toward its mission to solve all disease.
You will be responsible for financial management of all drug development-related work from discovery through preclinical testing. Key responsibilities include:
**Business & Financial Partnering:** Serve as the primary finance partner for the Drug Design and Development team, providing strategic thought partnership to support portfolio delivery objectives.
**Budgeting and Forecasting:** Lead end-to-end budgeting, forecasting, and resource planning for the drug development organization.
**Program and Asset Economics:** Provide financial decision support to the Portfolio Steering Team. Build project-level NPV and risk-adjusted valuation models for pipeline assets to support portfolio prioritization. Partner with Business Development to model economics for biopharma partnerships, licensing deals, research collaborations, and milestone structures.
**Research Oversight & Advisory:** Partner with the External Research team and Procurement during RFP processes to evaluate, benchmark, and negotiate budgets with vendors.
**Reporting & Process Improvement:** Deliver regular variance analysis and continuously enhance financial reporting and workflows to support portfolio growth. Oversee robust and efficient accruals processes.
You will bring financial thought leadership and rigor to key stakeholders, acting as a bridge between science and finance. The ideal candidate is a collaborative partner who builds trusting relationships across all levels, a proactive problem solver with curiosity and resourcefulness, detail-oriented with strong organizational skills, and a self-starter focused on streamlining processes and leveraging technology—particularly AI—to increase efficiency.
**Requirements:**
**Essential:**
- Direct experience managing R&D/drug development finance and FP&A/partnering within biotech, pharma, or life sciences
- Deep experience building and maintaining robust financial models for portfolio prioritization and project NPV analysis
- Degree in Finance, Accounting, Economics, or other quantitative field
- Clear executive-level communication skills for both technical and non-technical audiences; strong attention to detail and ability to manage competing priorities in a fast-paced environment
- Proven track record in business partnering, influencing senior leadership, and excellence in stakeholder management
- Experience utilizing LLMs and other AI tools to drive efficiency
**Nice to Have:**
- Professional accounting qualification (ACA, ACCA, CIMA, CPA, or equivalent)
- Life sciences background or experience
- Experience with Google Workspace (Sheets, Slides, etc.)
- Experience implementing or managing financial systems (ERP, procurement)
The role requires hybrid working with 3 days per week in the London office (currently Tuesday, Wednesday, and one additional day depending on team assignment).
