SlipstreamJobs tracks this role from the company's public career site. Apply directly on the employer's site.
Isomorphic Labs is seeking a Senior Finance Business Partner to serve as the dedicated financial strategic partner to the Clinical Development team. This is a new role supporting the growing clinical operations based in Cambridge, MA, as the company progresses medicines into the clinic.
You will be responsible for comprehensive financial management of all clinical-related work, including budgeting, forecasting, vendor oversight, and financial reporting. As the first finance hire in Cambridge, you will also act as the site finance lead, partnering closely with site leadership.
Key responsibilities include:
- Serving as the primary finance partner for Clinical Development, providing strategic thought partnership to support portfolio objectives
- Guiding end-to-end clinical budgeting, forecasting, and resource planning; building and maintaining bottoms-up financial models for clinical studies (site activations, patient enrollment, pass-through costs, etc.)
- Partnering with Clinical Operations and Procurement during RFP processes to evaluate, benchmark, and negotiate budgets with clinical vendors; supporting vendor onboarding, invoice review/approval, and P2P processes
- Delivering regular variance analysis and continuously enhancing financial reporting and workflows to support portfolio growth; developing robust and efficient accruals processes
- Acting as Cambridge site finance lead and partnering closely with site leadership team
The role requires someone who is a collaborative partner, proactive problem solver, detail-oriented, and growth-focused. You will bridge between science and finance, bringing financial thought leadership and rigor to key stakeholders.
Isomorphic Labs applies frontier AI to unlock deeper scientific insights and faster breakthroughs in drug discovery. Founded in 2021, the company has built a world-leading drug design engine comprising AI models capable of working across multiple therapeutic areas and drug modalities.
Hybrid working: 3 days per week in office (Tuesday, Wednesday, and one additional day).
QUALIFICATIONS:
Essential:
- Direct experience managing clinical development finances (CROs, sites) and FP&A/partnering within biotech, pharma, or life sciences
- Deep experience in financial analysis including building and maintaining robust patient-driven financial models
- Degree in Finance, Accounting, Economics, or other quantitative field
- Clear executive-level communication skills for both technical and non-technical audiences
- Strong attention to detail and ability to manage competing priorities in a fast-paced environment
- Proven track record in business partnering and excellence in stakeholder management
- Experience utilizing LLMs and other AI to drive efficiency
Nice to have:
- Professional accounting qualification (ACA, ACCA, CIMA, CPA, or equivalent)
- Experience using Google Workspace (Sheets, Slides, etc.)
- Experience managing financial systems (ERP, procurement)
