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Salary: USD 81,200 - 150,800 / annual
Mariana Oncology is seeking an experienced Research Scientist in Radiochemistry to join the Radiopharmacology function. This laboratory-based role supports the development of personalized medicine and radiopharmaceuticals through radiochemistry expertise, working with cross-functional project teams to generate critical data that advances product development.
Key responsibilities include performing radiolabeling of new product candidates, conducting product analysis and stability assessments, and supporting in vitro and in vivo biodistribution studies. You will work closely with Biology, Chemistry, and Pharmacology teams to identify and execute studies necessary for product advancement, including cell binding assays, in vitro efficacy studies, and in vivo biodistribution and efficacy studies. The role involves maintaining comprehensive records in an Electronic Lab Notebook, following SOPs and regulatory guidelines in a highly regulated environment, and ensuring compliance with health, safety, and environmental requirements.
You will communicate findings to cross-functional teams through data presentations and written reports, interface with internal teams and external collaborators/CROs, and mentor co-ops, interns, and junior associates. Additional responsibilities include contributing to protocol refinement, supporting in vivo studies as needed, and managing CRO relationships where applicable.
Desired but non-required skills include cell culture knowledge, experience with radioactive materials (training provided), and prior radiopharmaceutical experience (training provided for motivated candidates).
Requirements:
- Bachelor's degree in a relevant scientific field plus 2–5+ years of experience, OR Master's degree in a relevant scientific field plus 1+ year of experience
- Background in chemistry or radiochemistry
- Interest or experience in pharmacology and/or pharmacokinetic (PK) research
- Strong technical writing and oral communication abilities
- Proficiency with computers and software applications (Microsoft Office)
- Ability to work effectively in a small team setting and take on significant daily operational responsibilities
