SlipstreamJobs tracks this role from the company's public career site. Apply directly on the employer's site.
Salary: USD 75,000 - 105,000 / annual
Artiva Biotherapeutics is a clinical-stage biotechnology company developing natural killer (NK) cell-based therapies for autoimmune diseases. The company's lead product, AlloNK®, is a non-genetically modified, cryopreserved NK cell therapy being evaluated in combination with B-cell targeted monoclonal antibodies.
In this Manufacturing Associate role, you will work directly on the manufacturing floor in a state-of-the-art cGMP facility to produce innovative, off-the-shelf cell therapies. You will execute hands-on manufacturing processes across cell culture, aseptic processing, harvest, and fill-finish operations, playing a direct role in advancing therapies for patients.
Key responsibilities include:
- Execute GMO manufacturing operations including cell expansion, harvest, and fill-finish
- Perform Aseptic Process Validation and participate in annual aseptic qualification
- Follow cGMP standards and procedures to maintain compliance
- Support development of batch records, workflows, and SOPs in accordance with regulatory and GMP requirements
- Apply cell culture expertise to media/buffer preparation, cell passaging, bioreactor production, and harvesting
- Lead after-action reviews to improve operational efficiency and KPIs, identify process gaps/risks, and implement sustainable improvements
- Support equipment and process change controls through implementation
- Work in Grade B and Grade C cleanroom environments
- Perform hands-on manufacturing operations directly on the floor
You will work with cells and cell lines of human origin and must be able to stand and work gowned for prolonged periods.
QUALIFICATIONS:
- Bachelor's degree in a relevant science or engineering discipline, or equivalent work experience
- Minimum 1 year of cGMP biologics or cell culture manufacturing experience; biotech or cell therapy experience preferred
- Preferred experience with: aseptic gowning and ISO 7 cleanroom manufacturing, cell counting platforms, cell culture and expansion using bag systems and single-use large-scale bioreactors (Sartorius experience a plus), lentiviral transduction, automated and manual cell harvesting/washing (LOVO experience a plus), cell selection/depletion using Miltenyi CliniMACS Prodigy, fill-finish and cryopreservation in bags and vials (M1 filler and AT-vial experience a plus)
- Knowledge of cGMP regulations and FDA guidance applicable to biologics and cell therapy manufacturing
- Innovative, adaptable, and able to apply best practices in a small, growing environment
- Self-motivated with strong ownership, organizational skills, and the ability to prioritize and deliver results on time
