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Salary: USD 84,000 - 103,000 / annual
Strand Therapeutics is a clinical-stage biotechnology company pioneering programmable mRNA therapeutics. The company applies its proprietary Signal Stack platform—integrating EverScript circular RNA, AmpliScript self-replicating RNA, SignalPath targeted delivery, and SignalLock genetic circuits—to enable precise control of therapeutic activity and overcome limitations in targeting, durability, and safety. Strand is advancing a pipeline focused on oncology and autoimmune disease, with initial program STX-001 demonstrating preliminary evidence of systemic immune activation and anti-tumor activity in patients with advanced solid tumors. The company has raised over $250 million and is headquartered in Boston, founded by MIT synthetic biology pioneers.
In this role, you will be a highly contributing member of a small, productive team in a matrix-based environment. You will report to the Scientist of Cellular Analytical Development and serve as a strategic thinker bringing leadership presence and enthusiasm to the organization.
Primary responsibilities include: running and developing cell-based mRNA and LNP analytical methods; assisting in transfer of cell-based methods to external collaborators; using statistical tools to analyze data and independently draw conclusions; and providing analytical support to screening, optimization, and scale-up efforts in mRNA and LNP Process Development.
The role requires conducting laboratory experiments, excellent documentation review and writing skills, and flexibility to work on multiple projects. You will work in a fast-paced, entrepreneurial, team-focused environment with professional development support.
QUALIFICATIONS:
- B.S. or advanced degree in Biology, Biochemistry, Molecular Biology, Chemistry, Chemical Engineering, or other relevant scientific discipline
- 3+ years of experience with cell-based assays and their various readouts (ELISA, PCR, flow cytometry, etc.) required
- Experience with mammalian or ex-vivo tissue culture required
- Understanding of enzymatic and chemical reactions, PCR, plasmid processing, and standard analytical techniques for biologics or nucleic acid therapies
- Strong pluses: flow cytometry-based assay development, T cells and other primary cell culture, immunology, late clinical stage cell-based potency assays, Benchling template making and data handling, automation
- Familiarity with process development and/or regulatory aspects of mRNA-(lipid) nanoparticle products would be a plus
- Ability to quickly adapt to change and thrive in a dynamic, early-stage environment
- Strong team player with excellent oral and written communication skills and demonstrated ability to work independently
- Independently motivated, detail-oriented, with good problem-solving ability and excellent organizational skills
