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Salary: USD 223,000 - 261,000 / annual
Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect against bacterial diseases including invasive pneumococcal disease, Group A Strep, and Shigella.
You will lead assigned commercialization workstreams and facilitate overall launch readiness and commercial supply of polysaccharides used in glycoconjugate vaccines. This role focuses on technical launch planning and execution by bringing best practices and coordinating cross-functional efforts for regulatory filings, facility readiness, and launch supplies.
Key responsibilities include:
• Provide strategic and scientific leadership for polysaccharides with internal and external stakeholders, translating strategy into execution plans and ensuring completion of key technical milestones.
• Develop technical capabilities within the polysaccharide commercialization organization and support resource and staffing recommendations to achieve program objectives.
• Continuously improve process understanding and robustness using staff and laboratory resources to monitor, trend, and optimize operations.
• Coordinate cross-functional deliverables across Regulatory, CMC, Quality, Supply Chain, Procurement, and Process Engineering to drive successful development and commercial launch of polysaccharides. Identify, communicate, and escalate technical and supply risks that may impact program execution or commercial supply.
• Ensure robust processes exist to support technical transfers and integration of new technologies, providing technical oversight to support successful execution across internal and external manufacturing sites.
• Support the internal and external manufacturing network, including materials management and data analytics, and provide technical oversight of CMOs to support reliable manufacturing and commercial supply.
• Provide leadership for execution of process validation and process comparability activities. Effectively communicate the scientific and commercial rationale for polysaccharide processes to the Manufacturing organization and regulatory boards.
• Engage in technical review and authoring of regulatory filings and respond to questions from health authorities.
• Effectively communicate process performance to key stakeholders, both internal and external, building strong working relationships with emotional intelligence and clear, persuasive communication.
• Lead assigned polysaccharide commercialization programs and technical workstreams, coordinating execution across stakeholders as a member of the Global Manufacturing Operations organization.
• Travel 10-30% as required.
You will report to the Senior Director, Global Polysaccharide Commercialization Lead.
REQUIREMENTS:
• Degree in Chemical or Biochemical Engineering, Chemistry, Biochemistry, or related discipline with minimum 10+ years of relevant experience for Ph.D., 12+ years for M.S./M.A., or 16+ years for B.S./B.A.
• Extensive experience in biologic production processes, including bacterial fermentation, recovery, and purification across multiple operational scales. Experience with polysaccharides and glycoconjugate vaccines highly preferred.
• Leadership experience in MSAT (Manufacturing Science and Technology) or Process Development in supervisory and/or matrixed team roles.
• Ability to leverage deep technical knowledge in a collaborative manner to establish strategic plans and achieve collective goals.
• Excellent organization, problem-solving, and strategic planning skills.
• Highly skilled in both verbal and written communication with ability to interact effectively with people of diverse backgrounds and perspectives.
• Proactively recognizes needs and potential challenges, and directs activities to implement effective solutions.
• Ability to seek and analyze data from a variety of sources to support decisions and align others with the organization's overall strategy.
• Entrepreneurial and creative approach to developing new, innovative ideas that stretch the organization and push industry boundaries.
