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Salary: USD 108,000 - 120,000 / annual
Vaxcyte is a clinical-stage vaccine innovation company developing high-fidelity vaccines to protect against bacterial diseases including invasive pneumococcal disease, Group A Strep, and Shigella. The company is seeking an Associate Scientist II to support the Research Department in executing large and complex experimentation focused on vaccine formulation and process development.
In this role, you will work under the direction of senior scientists and staff scientists to conduct and coordinate pre-formulation and formulation studies, including bio-characterization studies, excipient screening, and short- and long-term stability studies. You will be responsible for running assays such as protein concentration, pH, and visual assessments to support the team's testing needs. You will assist senior scientists in developing analytical methods for biocharacterization of large molecules using techniques such as DSC, CD, and SEC. Additionally, you will support process development initiatives across ongoing research projects and contribute to troubleshooting efforts that remove roadblocks for early-stage pipeline projects.
You will maintain scientific accuracy and excellent written records of all experiments using Vaxcyte's ELN system. This position reports to the Staff Scientist in the Formulation and Process line within the Research Department and requires significant collaboration with the Analytical and other research teams. The role demands agility in both thought processes and practical execution, with encouragement to be scientifically proactive within the small group.
The position is based in San Carlos, CA, with a minimum of 4 days per week onsite.
REQUIREMENTS:
- BA/BS in Pharmaceutical Sciences, Organic/Biochemistry, Chemical/Biochemical Engineering, Biology, or related discipline with minimum 2 years of industrial experience; OR MS in one of these disciplines with minimum 1 year of industrial experience
- Experience in preparation of buffers and lab reagents (required)
- Experience in basic biological characterization techniques preferred, including pH, Nanodrop, biochemical assays, and particle size determinations
- Highly efficient and structured work practices including practical laboratory work, notebook upkeep, data generation, and presentation to research and wider teams
- Experience with analytical software such as Excel for data entry, maintenance, and analysis; understanding of analytical statistical analysis preferred
- Attention to detail and excellent skills in pipetting and sample preparation
- Demonstrated ability to work collaboratively in a cross-functional team environment on multiple projects
- Strong interpersonal skills with excellent written and verbal communication skills
