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Associate Scientist II, Analytical Development & Operations

Strand Therapeutics - Boston, MA, United States - In-office - posted 2026-10-20

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Salary: USD 81,000 - 89,000 / annual

Strand Therapeutics is a clinical-stage biotechnology company developing programmable mRNA therapeutics using its proprietary Signal Stack platform. The company integrates circular RNA, self-replicating RNA, targeted delivery, and genetic circuits to enable precise control of therapeutic activity. Strand is advancing a pipeline focused on oncology and autoimmune disease, with lead programs STX-001 (in clinical trials) and STX-003 (expected to enter clinic mid-2026). The company was founded by MIT synthetic biology pioneers, has raised over $250 million, and is headquartered in Boston. As Associate Scientist II of Analytical Development & Operations, you will support analytical development and testing efforts across screening, optimization, and scale-up initiatives. You will report to the Principal Scientist of Analytical Development and work closely with the founding team in a small, entrepreneurial environment. Key responsibilities include: - Analyzing internally and externally submitted samples using various analytical methods (cell-based assays, ELISAs, RT-PCR, LC-MS, etc.) - Supporting development of analytical methods and novel analytical techniques for physical characterization of early/clinical-stage mRNA and LNP formulations - Using statistical tools to analyze data and independently draw conclusions - Providing analytical support to mRNA and LNP Process Development teams for screening, optimization, and scale-up efforts The role offers a fast-paced, team-focused environment with professional development opportunities, work/life flexibility, and benefits including health/dental/life insurance, open PTO, onsite lunch catering, and commuter support. Qualifications: - B.S. or Advanced Degree with 2+ years of relevant experience required - Working experience in analytical development operations pertaining to biologics required - Prior experience with LNPs with nucleic acid payloads required - Experience with analytical methods such as cell-based assays, ELISAs, RT-PCR, and/or LC-MS preferred - Familiarity working with a Process Development team is a plus - Strong collaboration and interpersonal skills - Ability to multitask and prioritize to meet important deadlines

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